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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Cucurbitacin B Influence on cell viability MTT 0.01 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability MTT 0.03 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability MTT 0.05 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability MTT 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability MTT 1.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability MTT 10.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability MTT 20.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability MTT 40.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability MTT 60.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability MTT 80.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability AO/EB staining fluorescen microscopy 0.01 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability AO/EB staining fluorescen microscopy 0.05 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability AO/EB staining fluorescen microscopy 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability AO/EB staining fluorescen microscopy 1.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability AO/EB staining fluorescen microscopy 10.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell viability AO/EB staining fluorescen microscopy 40.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell apoptosis AO/EB staining fluorescen microscopy 0.01 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell apoptosis AO/EB staining fluorescen microscopy 0.05 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell apoptosis AO/EB staining fluorescen microscopy 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell apoptosis AO/EB staining fluorescen microscopy 1.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell apoptosis AO/EB staining fluorescen microscopy 10.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell apoptosis AO/EB staining fluorescen microscopy 40.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell necrosis AO/EB staining fluorescen microscopy 0.01 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell necrosis AO/EB staining fluorescen microscopy 0.05 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell necrosis AO/EB staining fluorescen microscopy 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell necrosis AO/EB staining fluorescen microscopy 1.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell necrosis AO/EB staining fluorescen microscopy 10.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on cell necrosis AO/EB staining fluorescen microscopy 40.00 µM HCT-116 Homo sapiens
Cucurbitacin B Cytotoxicity effect LDH release assay 0.01 µM HCT-116 Homo sapiens
Cucurbitacin B Cytotoxicity effect LDH release assay 0.05 µM HCT-116 Homo sapiens
Cucurbitacin B Cytotoxicity effect LDH release assay 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on DNA synthesis BrdU incorporation-ELISA 0.01 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on DNA synthesis BrdU incorporation-ELISA 0.05 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on DNA synthesis BrdU incorporation-ELISA 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on DNA fragmentation ELISA 1.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on DNA fragmentation ELISA 10.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on DNA fragmentation ELISA 40.00 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on protein level ELISA 0.01 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on protein level ELISA 0.05 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on gene expresion RT-qPCR 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on gene expresion RT-qPCR 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on gene expresion RT-qPCR 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on gene expresion RT-qPCR 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on gene expresion RT-qPCR 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on gene expresion RT-qPCR 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on protein levels Western Blot 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on protein levels Western Blot 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on protein levels Western Blot 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on protein levels Western Blot 0.50 µM HCT-116 Homo sapiens
Cucurbitacin B Influence on protein levels Western Blot 0.50 µM HCT-116 Homo sapiens